Struggling with tired, dull or crepey skin that hydration alone hasn’t fixed?
Elite Skin Clinic offers Polynucleotide (PDRN) treatment — a regenerative injectable that works at a cellular level to repair and rejuvenate skin
from within, available at our doctor-led clinic near Paddington, Marble Arch. Polynucleotides, also called PDRN or salmon DNA skin boosters, are especially effective for thin, crepey skin under the eyes and on the neck.
WHY CHOOSE POLYNUCLEOTIDE TREATMENT?
• Regenerative, Not Just Hydrating: Unlike standard skin boosters, Polynucleotides stimulate the skin’s own
repair and collagen-producing processes, rather than simply adding moisture.
• Ideal for Delicate Areas: Particularly effective for thin, fragile skin such as under the eyes, where other
injectables are less suitable.
• Doctor-Led Precision: Every treatment is delivered by a GMC-registered doctor following a full consultation.
• Minimal Downtime: Small bumps or mild redness typically settle within a day or two, with no significant recovery time needed.
TREATMENT SUMMARY
Treatment Time 30 minutes
Recovery / Downtime Minimal — 24–48 hours for any
mild swelling
Results Improved hydration, elasticity and
skin repair, building over 2–4 weeks
Risks Redness, swelling, bruising, small
bumps at injection sites
Anaesthetic Topical numbing cream available
Specialist GMC-registered doctor
Results Duration 6 months+, maintained with
periodic sessions
How Many Treatments Course of 2–3 sessions, 2–4 weeks apart
Polynucleotide vs. Profhilo: Which is Right for You?
Both are injectable skin-quality treatments, but they work differently. Profhilo is a high-concentration stabilised hyaluronic acid treatment, focused on deep hydration and stimulating collagen/elastin through tissue hydration — best suited to broader areas of the face and neck.
Polynucleotides work through a regenerative mechanism, supporting cellular repair and fibroblast activity directly, and are particularly well-suited to more fragile or thin skin, such as the under-eye area, where Profhilo is less commonly used.
Many patients combine both as part of a broader skin health plan — Polynucleotides for regeneration in delicate areas, Profhilo for overall hydration elsewhere on the face. Consider your specific concern and consult with our doctors at
Elite Skin Clinic to find the best option for your needs.
HOW DOES THE TREATMENT WORK ?
Your treatment begins with a full consultation with one of our GMC-registered doctors, who will assess your skin and confirm whether Polynucleotides are the right treatment for your goals. A series of small injections then deliver the Polynucleotide solution into the targeted area — most commonly the under-eye area, cheeks, neck or décolletage. The treatment takes around 30 minutes, with topical numbing cream available for comfort.
FREQUENTLY ASKED QUESTIONS
Are Polynucleotides safe? Polynucleotides have a long history of medical use in wound healing and tissue repair, and are considered well-tolerated when administered by a trained medical professional.
Do Polynucleotide injections hurt? Most patients describe mild discomfort, similar to other fine-needle injectable treatments. Topical numbing cream is available for comfort.
How many sessions will I need? Most patients benefit from a course of 2–3 sessions spaced 2–4 weeks apart, followed by maintenance sessions roughly every 6 months.
Can Polynucleotides be combined with other treatments? Yes — commonly combined with Profhilo, dermal filler, or anti-wrinkle injections as part of a broader treatment plan, depending on your goals.
Is there any downtime? Minimal — mild swelling or small bumps at injection sites typically settle within a day or two.
Who shouldn’t have Polynucleotide treatment? Patients with a known fish allergy, pregnant or breastfeeding patients, or those with active skin infections in the treatment area should not proceed without further medical assessment.
Save Big: Polynucleotide Treatments in London!
Polynucleotide Treatment for face starts from £219
Polynucleotide Treatment for eyes starts from £199
PRE-CARE AND AFTER-CARE FOR POLYNUCLEOTIDE TREATMENT
Pre-Care: 1. Stay well hydrated in the days before treatment. 2. Avoid blood-thinning medication or supplements (aspirin, ibuprofen, fish oil) for about a week beforehand, if medically appropriate. 3. Have a thorough consultation to
discuss medical history, including any fish allergy, given the biological origin of the product.
After-Care: 1. Avoid touching or applying makeup to the treated area for a few hours. 2. Avoid saunas, steam rooms
and intense exercise for 24–48 hours. 3. Mild redness or small bumps typically settle within a day or two. 4. Stay
hydrated and use daily SPF to support and prolong results.
Why Choose Elite Skin for Polynucleotides
Elite Skin Clinic is a doctor-led aesthetic clinic based at Marble Arch Medical Centre, London W2. Every Polynucleotide treatment is delivered by a GMC-registered doctor following a full consultation — never a walk-in, beautician-led, or nurse-only appointment. If Polynucleotides aren’t the right fit for your goals, we’ll tell you, and recommend what would serve you better instead.
If you’d like more information about our features, get in touch today.
